What is Andrographolide?

Andrographolide is a labdane diterpenoid that is produced by the Andrographis paniculata plant, which has a broad range of therapeutic applications including and anti-platelet aggregation activities and potential properties. Since andrographolide has multiple therapeutic activities there are several proposed mechanisms of action for this agent. The effects of this agent appear to be related to the inhibition of nitric oxide (NO) production by macrophages.

This agent may activate the NO/cyclic GMP pathway and inhibit both the phospholipase C gamma 2 (PLC gamma2)/protein kinase C (PKC) and PI3K/AKT-MAPK signaling pathways in activated platelets to inhibit platelet aggregation. In activated platelets, these three signaling pathways are downstream of integrin activation mediated by collagen binding and influence the association of fibrinogen with its receptors. Additionally, andrographolide may exert its activity through the induction of cell cycle arrest at G0/G1 phase and the stimulation of lymphocyte proliferation and activation. These processes could result in decreased proliferation of and increased immunocytotoxicity against tumor cells.

Basic Information:

Andrographolide Benefits:

Normal virus. Taking andrographis by mouth, alone or as a feature of a natural blend item, appears to further develop hack and sore throat in certain individuals with the normal virus. It's not satisfactory if andrographolide assists with forestalling colds.

Osteoarthritis. Taking andrographis separate by mouth everyday appears to lessen agony and solidness in individuals with gentle or direct osteoarthritis in the knee.

Disease of the throat and tonsils (tonsillopharyngitis). Taking andrographolide powder by mouth day to day works comparably well as acetaminophen (Tylenol) to lessen fever and agony from tonsillitis.

A sort of fiery gut infection (ulcerative colitis). Taking andrographis extricate by mouth day to day for quite some time decreases side effects of ulcerative colitis similarly well as the medication mesalamine.

Andrographolide Application

1. Applied in pharmaceutical field, it is usually made into tablets, soft capsule, injectio, etc. to treat acute bacillary dysentery, gastroenteritis, cat fever, amygdalitis, faucitis, bronchitis, pneumonia, phthisis and so on.

2. Applied in veterinary field, it is made into pulvis to treat acute bacillary dysentery, gastro-enteritis and pneumonia of poultry and livestock.

The Best andrographolide manufacturer

Undersun enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our products, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our products on-time.

We also focus on value-added services. We are available for service questions and information to support your business.

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