What is Citrus Aurantium Extract?

Citrus aurantium extract refers to the bitter orange fruit. The juice, peel, and pulp can be taken orally. They have been used to ease anxiety, digestion, and sleeplessness. Citrus aurantium has also been used to promote weight loss. It can be applied to the skin or diffused as an oil. Citrus aurantium can also be made into a tea or taken as a pill, powder, or citrus aurantium extract.

Citrus aurantium extract has been largely used in weight loss and sports performance dietary supplements. However, the safety of C. aurantium-containing products has been questioned mainly due to the association of its use with adverse events in the cardiovascular system. Therefore, this work aimed to assess the potential for herb-drug interactions among a standardized C. aurantium extract and amiodarone (narrow therapeutic index drug) in rats. In a first pharmacokinetic study, rats were simultaneously co-administered with a single-dose of C. aurantium (164 mg/kg, p.o.) and amiodarone (50 mg/kg, p.o.); in a second study, rats were pre-treated during 14 days with C.

Analysis:

Citrus Aurantium Extract Benefits:

The efficacy of flavonoids and flavonoid-rich extracts in treating varicose veins is related to their ability to:
(1)It reduces capillary fragility,
(2)It increases the integrity of the venous wall,
(3)It inhibits the breakdown of the compounds composing the ground substance, and
(4)It increases the muscular tone of the vein.

Citrus Aurantium Extract Application:

1. As Food and beverage ingredients.
2. As Healthy Products ingredients.
3. As Nutrition Supplements ingredients.
4. As Pharmaceutical Industry & General Drugs ingredients.
5. As a health food and cosmetic ingredients

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