Cranberry extract proanthocyanidins are widely available and the most common way to treat infections of the urinary tract. However, for the cranberry extract to be effective, the concentration of proanthocyanidins (PACs) must be uniform. Normalization ensures the amount of the dynamic piece of the fixing: the PACs' in this instance.
A class of proanthocyanidins known as A-type PACs, which have been shown to effectively inhibit bacterial adhesion and aid in the prevention of urinary tract infections (UTIs), are abundant in cranberries. An adult women's multicenter randomized clinical trial (RCT) found that a daily dose of 36 mg or more of PACs provided the best effect.
Item | Specification | Test Method |
Physical&Chemical Control | ||
Appearance | Violet Fine Powder | Visual |
Odor&Taste | Characteristic | Organoleptic |
Assay | Proanthocyanidins≥50% | UV(EP Standard) |
Particle size | 100% pass 80 mesh | 80 Mesh Screen |
Identification | Positive | TLC |
Loss on drying | ≤5.0% | CP2015 |
Heavy Metals | ||
Heavy Metals | NMT10ppm | Atomic Absorption |
Lead(Pb) | NMT3ppm | Atomic Absorption |
Arsenic (As) | NMT2ppm | Atomic Absorption |
Mercury(Hg) | NMT0.1ppm | Atomic Absorption |
Microbiology Control | ||
Total Plate Count | NMT3,000cfu/g | CP2015 |
By reducing adhesion, biofilm, and co-aggregation, cranberry extract proanthocyanidins and other constituents interact with a wide range of bacteria, including gut microbes that cause urinary tract infections (UTIs) and other health conditions. Inflammatory bowel disease (IBD), which is characterized by persistent gut inflammation, has been linked to genetic factors, lifestyle, and dietary habits that raise the risk of colon cancer.
Devouring food varieties high in calming and cell reinforcement compounds, for example, polyphenols or dietary fiber, may consequently give a precaution system to relieve these circumstances and decrease colon malignant growth risk. Utilizing a DSS-AOM (dextran sodium sulphat - azoxymethane) mouse model of colitis-prompted colon tumorigenesis, past examinations by us showed a critical decrease in colon growths and tissue irritation in mice took care of either entireproanthocyanidins cranberry or cranberry separates rich in either polyphenols or non-polyphenol constituents of cranberry.
Various mixtures in cranberries including flavonoids, cranberry proanthocyanidins and triterpenoids have likewise been accounted for to diminish cancer cell development and multiplication, animate apoptosis, prompt cell cycle capture, and change related flagging cycles in cells.
1. Applied in pharmaceutical field, to be used as raw material;
2. Applied in health-care product field, to be used for keeping body healthy;
3. Applied in food field, to be used as nutritional supplement.
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