What is Eleutheroside?

Eleutherosides are a diverse collection of chemical compounds derived from the roots of the herb Eleutherococcus senticosus, which are primarily sold as extracts in the marketplace. Other eleutherosides, like eleutheroside B (syringin), are phenyl propanoid glycosides, while eleutheroside A is a saponin and sterol glycoside. They are used to identify Eleutherococcus senticosus herbal preparations and dietary supplements using thin layer chromatography as marker compounds.

Eleutheroside E is an optical isomer of acanthoside D, which is the di-D-glucoside of ()-syringaresinol and one of the glycosides that was isolated from the cluster-flowering acanthopanax.

Basic Information:

Eleutheroside Benefits:

Fatigue
According to a 2009 review of the literature that was published in Current Clinical Pharmacology3, eleutheroside may help people with mild, stress-induced fatigue improve their mental performance. Additionally, a 2004 study from Psychological Medicine found that eleuthero may benefit people with "moderate fatigue." However, the study also found that eleuthero did not help people who were extremely tired.

Osteoarthritis

In a 2009 study that was published in The Korean Journal of Physiology and Pharmacology, researchers assigned 57 patients with knee osteoarthritis to six weeks of daily treatment with either a placebo or an herbal formula containing eleuthero, eleutherosides, and Chinese foxglove. Each of the participants in the study received either eleutherosides or a placebo for two months.4 Osteoarthritis By the end of the study, compared to those who took the placebo, those who took the herbal formula showed greater improvement in pain and physical functioning. However, it is unknown if eleuthero can assist in the management of osteoarthritis on its own.

Eleuthero may help lower cholesterol

according to a 2008 study in Biochemical and Biophysical Research Communications. For the duration of the study, 40 postmenopausal women were given either calcium alone or calcium plus eleutheroside. According to the findings of the study, individuals who received calcium plus eleuthero experienced significant reductions in LDL cholesterol as well as certain markers of oxidative stress, which is a harmful biological process linked to numerous major health issues, including cancer and heart disease.6

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