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What is Horse Chestnut Seed Extract?

Horse chestnut seed extract is extricated from the dried seeds of Aesculus Hippocastanum L.

Standardized horse chestnut seed extract is a deciduous tree, local to the Balkans, western Asia and the Himalayas; it has been presented and presently fills in a large part of the mild world.

Utilizes: A decoction or mixture of the spice powder can be added to creams and treatments for drained and hurting legs. Horse Chestnut Seed Powder can help with furnishing solace while managing enlarging or irritation of joints and muscles.


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Basic Information:

Product Name

Horse Chestnut Extract Aescin

Other name


Aescin

Part of used

Bark

Form

Powder

Appearance

Brown yellow powder

Specification

20%

MOQ

1kg

Active Ingredient

Esculin

Loss on drying

<3.0%

Testing Method

HPLC

Item

Specification

Result


Appearance

White crystalline powder

Complies


Related substance (HPLC)

Total impurity ≤0.5%

Max single impurity ≤0.1%

0.2%

0.06%


Assay

20%

20.6%


Heavy Metal

<10ppm

Complies



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Horse Chestnut Seed Extract Benefits:

1. May Help Treat Chronic Venous Insufficiency

Chronic Venous Insufficiency, or CVI, is also known as post-thrombotic syndrome or phlebitis. This condition is characterized by non-functioning valves in your veins (commonly in the legs and sometimes arms), which causes blood to pool in the limbs and an increase in internal pressure within the veins.

CVI is actually a very common affliction, affecting up to as many as 40 percent of people in the U.S. It’s more common for women, particularly after multiple pregnancies, and in middle-aged and older adults. Varicose veins and blood clots (deep vein thrombosis) are risk factors for developing CVI.


2. Could Cause Cell Death in Certain Cancers

When cancer research is conducted on a particular substance, scientists begin by observing the effect of that substance on specific types of cancer cells in a lab. If the substance has a significant impact in causing the death of those cancer cells, future research may be warranted to see if it is a potential cancer treatment.

In a laboratory setting, horse chestnut seed extract has shown cancer-fighting effects on cells related to leukemia, cervical cancer and breast cancer. The most drastic of these were Jurkat cells, used to test a type of cancer known as acute T-cell leukemia, in which the lab tests found a cell death rate of nearly 94 percent.


3. Contains Powerful s

Extract of horse chestnut contains some incredible s, which can help your body to fight free radical damage and more effectively fight disease. Studies have discovered both quercetin and kaempferol glycosides in horse chestnut, two s praised for their intense disease-fighting capabilities.


4. May Increase Effects of Prebiotics

A lot of us know that good probiotic foods can aid in digestion and gut health, but did you know that by pairing those with prebiotics, you’ll gain even more digestive benefits? Prebiotics are a type of non-digestible fiber compound that are fermented by the gut microflora in the colon.

In 2011, a study was conducted using rats to find the efficacy of using horse chestnut seed extract and flaxseed oil to improve the effect of probiotics. Both of these natural substances made prebiotics more effective. Scientists conducting the study point out that prebiotics are useful agents to help prevent and treat colon cancer.


5. Possibly Beneficial in Wound Healing

Another benefit of horse chestnut that’s been a feature of preliminary research is its ability to help wounds heal. While no human studies have yet been conducted, a 2006 lab study found that standardized horse chestnut seed extract can help induce contraction forces in fibroblasts, cells integral to the wound healing process. When these fibroblasts contract, they potentially induce faster wound healing.

Again, this research is not conclusive and may not function as expected in humans, but these results are promising.


6. Might Support Fertility in Men

Due to the rate at which male infertility is increasing, it’s become more important than ever to understand ways to support and maintain healthy sperm counts.

Supplements of horse chestnut contain an ingredient called escin — not to be confused with the poisonous esculin found in raw standardized horse chestnut seed extract. Possibly through the same mechanisms with which horse chestnut positively impacts chronic venous insufficiency, escin seems to safely increase count and quality of sperm in men with varicocele-associated infertility, according to a 2010 research study.


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