Natural Berberine and Sanguinarine alkaloids belong to a group of naturally occurring chemical compounds that mostly contain basic nitrogen atoms. This group also includes some related compounds with neutral or weakly acidic properties. Alkaloids are produced by a large number of organisms including bacteria, fungi, plants, and animals.
Natural Berberine and Sanguinarine both are isoquinoline derivatives and belong to protoberberine and benzophenanthridines, respectively. Tyrosine or phenylalanine is common precursor for the biosynthesis of both. Sanguinarine [13-methyl (1,3) benzodioxolo(5,6-c)-1,3-dioxolo (4,5) phenanthridinium] is a toxin that kills animal cells through its action on the Na+-K+-ATPase transmembrane protein. Berberine, on the other hand, has been reported to cause cytotoxicity and adversely influence the synthesis of DNA.
Product Name | Berberine HCL Powder | Latin Name | Phellodendron amurense Rupr. |
Part Used | Bark | Appearance | Yellow Needle Crystal Powder |
Specification | 98% Berberine HCL Powder | ||
Function | 1. To remove damp-heat. 2. Quenching fire. 3. Counteracting toxicity. 4. Relieving consumptive fever. 5. Cortex Phellodendri ( Processed With Salt ):To nourish yin and reduce fire. | ||
Storage | Store in a well-closed container away from moisture and direct sunlight | ||
Shelf Life | 24 months if sealed and stored properly | ||
Sterilization Method | High-temperature, non-irradiated. |
“One way that natural berberine works is that it [may help] the body achieve a more healthier mix of gut flora,” Foroutan says. While more human studies need to be conducted to show this connection, several scientific studies, including this one published in the journal Drug Metabolism and Disposition, have shown this in mice. Specifically, the study found that when bacteria from mice’s lower intestine was exposed to berberine,, it “not only altered bacterial physiology but also changed bacterial community composition and function.”
2. It may help keep blood sugar levels steady
There is also some evidence to suggest that best quality berberine can help keep blood sugar levels in check. “Berberine activates an enzyme called adenosine monophosphate kinase (AMPK), which is an insulin-dependent process. This triggers a series of enzymes that helps the body transport glucose from the blood into muscles and other cells, effectively lowering blood sugar,” Foroutan explains. However, more robust clinical trials need to performed before this benefit is conclusive.
3. It’s good for your heart
Since the enzyme best berberine activates helps with blood flow, Foroutan says this means it could also be good for cardiovascular health. “Recent research has shown that berberine may protect against heart failure, high blood pressure, high cholesterol, insulin resistance, arrhythmias, and platelet aggregation,” Foroutan says. “It’s been found to lower cholesterol in people with high cholesterol, including ‘bad’ LDL cholesterol and triglycerides,” she adds. Again, much of the research on this subject was performed on animals, meaning that it’s not quite clear whether those benefits translate to humans.
4. Berberine supports liver function
Another benefit to natural berberine, according to Foroutan, is that it’s good for liver health. “Berberine has been found to improve liver enzymes in people with the common liver disease called non-alcoholic fatty liver disease (NAFL),” she says. This is because it may help the liver get rid of stored fat, which prevents it from functioning properly. In one randomized controlled trial published in the journal PLOS One, consuming berberine daily for 16 weeks was associated with reducing fat in the liver by as much as 53 percent.
5. Consuming berberine could improve your mood
Some scientific evidence shows a connection between consuming berberine and lowering depression. According to a scientific paper published in the European Journal of Pharmacology, the consumption of berberine by mice was associated with increased amounts of serotonin and dopamine, the “feel good” chemicals in the brain. While this is a promising connection, more human studies need to be done to establish a strong connection.
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The Best Natural Berberine Supplier
Undersun enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our products, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our products on-time.
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Why Choose Undersun Natural Berberine?
Undersun specialize in pure berberine for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.
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