What is Platycodon Root Extract?

Platycodon is a traditional Chinese medicinal herb used to expel pus, rid phlegm and disseminate Lung Qi. Platycodon supports respiratory health, benefits the throat, may promote healthy weight and benefit cognitive function. Platycodon Root contains , , , , expectorant and immune boosting properties.

The platycodon root extract and pure saponins from the roots of Platycodon grandiflorum (PG) are reported to have a wide range of health benefits. Platycosides (saponins) from the roots of PG are characterized by a structure containing a triterpenoid aglycone and two sugar chains. Saponins are of commercial significance, and their applications are increasing with increasing evidence of their health benefits. The biological effects of saponins include cytotoxic effects against cancer cells, neuroprotective activity, activity, and cholesterol lowering effects. Saponins with commercial value range from crude platycodon root extract, which can be used for their foaming properties, to high purity saponins such as platycodin D, which can be used for its health applications (e.g., as a vaccine adjuvant).

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Platycodon Root Benefits:

The platycodon grandiflorum root extract and purified platycoside compounds (saponins) from the roots of Platycodon grandiflorum may exhibit neuroprotective, , , , , improved insulin resistance, and cholesterol-lowering properties.

1. Hypoglycemic effect

In normal homes, taking Platycodon grandiflorum water or alcohol extract 200 mg/kg can reduce blood sugar, similar to tolbutamide. It also has a hypoglycemic effect on experimental tetrachloropyrimidine diabetic rabbits, and can inhibit the rise of food-induced blood sugar. The reduction of liver glycogen is also restored after treatment, and the effect of alcohol extract is stronger than that of water extract.

2. Expectorant, antitussive effect

Both the platycodon root extract and the root decoction can reduce the excretion of phenol red and have a very significant expectorant effect. The main reason is that the saponin contained in it stimulates the glossopharyngeal nerve terminals when administered orally, reflexively causes hypersecretion of the respiratory tract, and dilutes the sputum and makes it easy to cough up. Platycodin D and D3 may be effective phlegm-reducing ingredients. Studies have shown that Platycodon grandiflorum saponins capsules have obvious , relieving cough, relieving asthma and expectorant effects, and have certain preventive and therapeutic effects on chronic bronchitis.

3. and effects

Platycodon root extract petroleum ether extract has effect, its specific mechanism of action and the structure-activity relationship of Platycodon grandiflorum saponin activity need to be further studied.

4. Lower cholesterol effect

Platycodon grandiflorum saponin can increase the secretion of bile acid, reduce the cholesterol content in the liver of rats, and increase the excretion of steroids.

5. Hemolysis

Platycodon grandiflorum saponins have local irritation and strong hemolysis, with a hemolytic index of 887. Therefore, it can only be taken orally, not as an injection. Oral administration can hydrolyze and destroy saponins in the digestive tract without hemolysis. But when large doses are taken orally, saponins are used to stimulate the gastric mucosa, which can cause nausea and vomiting.

6. effect:

Platycodon grandiflorum water infusion and decoction are diluted by test tube, and 1:10 can inhibit epidermophyton flocculent in vitro. The decoction 4.50% flat small groove method can inhibit Staphylococcus aureus, typhoid bacillus, Shigella flexneri, Pseudomonas aeruginosa and Escherichia coli.

7. Calming, analgesic and effects

Platycodon grandiflorum crude saponin has strong and analgesic effects when fed to animals. Using typhoid vaccine to induce fever in mice, gavage at 50-100mg/kg, can reduce the spontaneous activity of mice, and has obvious effect And can be maintained for 3 to 4 hours.

8. Inhibit gastric acid secretion and anti-ulcer effect

Platycodon grandiflorum saponins can inhibit gastric juice secretion and resist peptic ulcer. To rats with pylorus ligation, platycodin administered to the duodenum can reduce the secretion of gastric juice and partially inhibit the activity of pepsin. Its inhibitory effect on experimental ulcers is similar to that of atropine. After increasing the dose, it can completely inhibit the secretion of gastric juice and the occurrence of ulcers. Continuous administration of crude platycodon saponins in rats can also reduce the occurrence of acetic ulcer. The platycodon root extract also has an anti-ulcer effect.

9. and immune enhancement effects

The crude platycodon saponins have effects. In addition, the crude platycodon saponins have a local stimulating effect on the skin, which can improve the inflammation and blood circulation, promote the improvement of inflammation and the absorption of the inflammatory process. Platycodon grandiflorum has immune function enhancement effect. Its extract can inhibit the migration of white blood cells, enhance the bactericidal power of neutrophils, and increase the activity of lysozyme; crude saponin can also enhance the phagocytic function of macrophages.

10. Other functions

Platycodon grandiflorum saponins have the effects of lowering blood pressure, slowing down heart rate, and inhibiting respiration. Its antihypertensive effect cannot be antagonized by atropine and alpha and beta blockers. It has anti-edema and diuretic effect on rats with congestive edema caused by bilateral jugular vein ligation. In addition, platycodon extract still has effects.

Platycodon Root Uses:

1. Balloon flower extract and purified platycoside compounds (saponins) from the roots of Platycodon grandiflorum may exhibit neuro-protective, , , , , improved insulin resistance, and cholesterol-lowering properties.

2. Roots are commonly used for treating bronchitis, asthma, hypertension, tuberculosis, diabetes, and other inflammatory diseases in Korea.

3. They are used as a cough suppressant and expectorant for common colds, cough, sore throat, tonsillitis, and chest congestion in China.

4. It is widely used there in patent remedies and is also made into cough tablets.

5. Platycodon root extract contains saponins and is anthelmintic, anti-asthmatic, anti-cholesterolemic, anti-phlogistic, antitussive, astringent, carminative, expectorant, haemolytic, hypoglycaemic, sedative, stomachic, tonic and vermifuge.

6. It lowers blood sugar and cholesterol levels in the liver and inhibits the release of histamine.

7. It is used internally in the treatment of coughs with profuse phlegm, colds, bronchitis, pleurisy, pulmonary abscesses and throat infections.

8. Its roots are used to treat sore throat, cough and other respiratory disorders.

9. Liver flukes are best cured by using balloon flower.

10. Platycodon grandiflorum root extract is consumed to maintain blood sugar and cholesterol level.

11. Nutrients present in its roots are useful for recovering from fatigue.

12. Chinese use its roots in medicines as it is a wonderful Anti- Inflammatory herb.

13. Water extract of the flower is used to heal ulcers.

14. Its root is a good herbal treatment for Allergies.

15. Root of the plant is used to treat cough, excessive mucus formation in the throat, sore throat, the common cold, flu, bronchitis, abscesses of the mouth and throat, dysentery and pains in the intestinal region.

16. Platycodon extract have been used as an treatment in folk medicines.

17. Korean research discovered that the saponins in the herb slowed down the growth of cultured human tumor cells.

18. Saponins can prevent gastric secretion and have ulcer-protective and ulcer-healing properties.

19. One Korean study found that the balloon flower root extract may have potential in treating allergies.

20. Balloon flower is one of the eight herbs found in the Japanese folk remedy “Sho-saiko-to-ka-kikyo-sekko” that is used to treat pharyngitis or acute tonsillitis.

21. Platycodon root extract combines Perilla Leaf and Apricot Seed for the treatment of common cold due to wind-cold.

22. This herb is used along with Licorice Root, Arctium, etc. for sore throat and aphonia caused by exogenous pathogenic factors invading the lung.

23. It works with Licorice Root to treat coughing up fishy phlegm.

24. Balloon flower root is often prescribed for loss of voice.

The Best Platycodon Root Extract Supplier

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We also focus on value-added services. We are available for service questions and information to support your business.

Why Choose Undersun platycodon grandiflorum root extract?

Undersun specialize in platycodon extract for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.

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