What is Salacia Reticulata Extract?

The plant salacia reticulata extract is native to Sri Lanka's dry zone forests and is a member of the Celastraceae family. Salacia reticulata is widely used in Ayurvedic traditional medicine to treat diabetes. Yoshikawa et al. collected the salacia reticulata extract ( in Sri Lanka in 2002. Under reflux, methanol extract of the 1.7 kg of powdered dried roots and stems was made.

Under reduced pressure, the salacia root extract was concentrated, and various solvents were used to make additional fractions. Through bioassay-guided separation, salacinol was extracted from salacia oblonga extract in this study. It had an IC50 value of 3.2 g/mL, making it the most effective inhibitor of the -glucosidase enzyme.

Basic Information:

Salacia Reticulata Extract Benefits

Weight loss
Salacia Reticulata Extract has been shown to normalize glucose or lipid metabolism, prevent fat accumulation, and promote the activity of genes that support fat breakdown in animals. According to research, the presence of salacinol, mangigerin, kotalanol, and kotalagenin 16-acetate is the cause of these properties. Salacia reticulata and cyclodextrin, according to animal studies, reduce the risk of weight gain, visceral fat, fat deposition, and cholesterol or lipid levels in obesity caused by a high-fat diet.

Prevent fat absorption

The enzyme known as lipase is essential for fat deposition and digestion. Extract from stems and leaves has been shown to inhibit lipase activity in studies. Strong inhibitory properties are demonstrated by polyphenolic compounds like methylepigallocatechin, mangiferin, epicathechin, and epigallocatechin. It prevents fat from being absorbed and metabolism. It makes it easier to break down fats and get rid of them.

Lowers cholesterol levels
Salacia Reticulata Extract have been shown in studies to effectively lower cholesterol and lipids. When taken for six weeks, 500 mg of leaf and root extracts help patients with mild and moderate hyperlipidemia lower their cholesterol and lipid levels. Research displays the cholesterol bringing down impact of root extricate showing comparable impact of simvastatin, an enemy of hyperlipidemic drug.

Anti-diabetic properties

Salacia reticulata extracts exhibit anti-diabetic properties by lowering blood glucose levels. The utilization of carbohydrates in diet is made possible by the equilibrium of insulin and glucose levels. It forestalls the augmentation in glucose levels after dinners and furthermore controls craving. Kotalanol and salacinol, two compounds found in Salacia Reticulata Extract, prevent enzymes like alpha-glucosidase from absorbing and digesting carbohydrates from the body. Root separates shows quicker activity in contrast with leaf extricate in bringing down glucose and cholesterol levels. A study demonstrates that a herb can be administered orally as a hypoglycemic agent to restore normal blood sugar levels following a meal high in carbohydrates. The consumption of Slacia reticulata-containing herbal tea aids in the reduction of blood glucose levels.

Hostile to stout movement

Salacia root extract assists with controlling issues related to weight. Patients who were obese participated in the study. The digestion of dietary fat requires the pancreatic lipase enzyme. In humans, it aids in weight loss. It is accounted for that S. reticulate assists with smothering pancreatic lipase action. It is a crucial mechanism for reducing postprandial hyperlipidemia because it prevents pancreatic lipase activity from occurring in the small intestine.

Anti-proliferative activity

In cells that have been activated by interleukin-1, the leaves of salacia oblonga extract exhibit anti-proliferative activity. In synoviocyte-like cell lines, an extract of 850 mg/ml inhibits matrix metalloproteinase genes by 50%. The findings indicate that Salacia has significant anti-proliferative activity.

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