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What is Senna Leaf Extract?

Senna Leaf Extract is a kind of plant raw material extracted from Cassia angustifolia Vahl., the main raw material of Senna Leaf dry leaflet, using the extraction technology of plant active ingredients. Its main active ingredients are Sennoside A and B (Sennoside A and B), and it contains anthraquinone derivatives such as emodin, aloe emodin, emodin and other glycosides.

Senna leaf extract is prepared from a large genus of flowering plant Cassia angustifolia Vahl in the fabaceae family on the tropics. It has been used for centuries in folk medicine as a laxative and stimulant. Senna is also included in several herbal teas, used for purging and in weight loss. The active components sennoside in senna leaf extract are anthraquinone derivatives and their glucosides, referred to as senna glycosides or sennosides.

Senna leaf extract weight loss belongs to a large genus of flowering plants found throughout the tropics, commonly used species being Cassia acutifolio (Alexandrian senna) and C. angustifolio (Indian or Tinnevelly senna). Extracts of the leaves, flowers and fruit of senna have been used for centuries in folk medicine as a laxative and stimulant. Senna is also included in several herbal teas, used for purging and in weight loss. The active components in it is anthraquinone derivatives and their glucosides, referred to as senna glycosides or sennosides.

Senna Leaf Extract

Basic Information:

PARAMETER

SPECIFICATION

Description

Light to dark brown Color Powder

Odour & Taste

Characteristic

Identification

Positive for Sennoside by TLC

Bulk Density ( tapped)

0.30 to 0.80 gm/ml

Loss on drying

NMT 5.0 %

pH of 1% Solution

5.0 – 8.0

Particle Size

100 % Pass through 40 mesh

Assay


Total sennosides by UV (As is)

NLT 20 %

Microbial Analysis


Total Plate Count

NMT 1000 cfu/gm

Yeast and Mould

NMT 100 cfu/gm

Coliforms

Absent

E. coli

Absent

Salmonella spp.

Absent

Shigella

Absent

Heavy Metal

NMT 10 ppm

Senna Leaf benefits

Senna Leaf Extract Benefits:


It is used to treat constipation and also to clear the bowel before diagnostic tests such as colonoscopy. Senna is also used for irritable bowel syndrome (IBS), anal or rectal surgery, tears in the lining of the anus (anal fissures), hemorrhoids, and weight loss. Senna fruit seems to be gentler than senna leaf.

1.Constipation

The most famous use of this herb is as a laxative and a purgative. It is now known that the laxative effects of Senna are due to anthraquinone glycosides known as sennosides. These compounds stimulate intestinal contractions that lead to the rapid expulsion of waste matter.

Senna may also be able to soften the stool by assisting the large intestine to absorb more water and adding bulk to faeces. This allows for bowel movements that are quick and smooth as waste passes through the large intestine.

2.Colon Cleanse

Senna Leaf Extract is often used to clear the bowel before diagnostic tests such as colonoscopies. Cleansing the colon is believed to improve nutrient uptake and support overall colon health.


3.Anti-Parasitic

Senna Leaf Extract also works as an effective vermifuge to destroy parasites and expel worms from the intestinal tract. It works best when combined with other anthelmintic herbs (used in the treatment of roundworm), such as ginger or fennel. These herbs increase regularity and reduce the chance of bowel cramps due to Senna’s strong action.


3.Digestive Health

In the case of indigestion, Senna contains natural enzymes that help to restore gastric juice secretions in the stomach. Senna, if used in the proper dosage for certain periods of time, has shown potential in reducing irritability in the intestines by improving overall digestion.Senna also contains the compound resveratrol which can help to soothe inflammation in the gastrointestinal tract.


4.Skin Health

Senna Leaf Extract contain essential oils and tannins that help to alleviate skin inflammation. With a strong activity, they can be made into a compress which can be applied to wounds and burns.


Acetone and ethanol - other compounds present in Senna - can fight the microorganisms that cause acne. Senna also helps to reduce sebum production and increase cell regeneration and collagen production.

senna leaf for weight loss

Senna is frequently marketed as a weight loss tool, but there's no evidence to support this effect. Due to its long-term health risks, you should not use senna to lose weight.

Senna Leaf Extract Dose

Senna Leaf Extract Dose

Dosage Forms and Strengths

Tablet, extended-release

8.6 mg

15 mg

25 mg

Chewable tablet

10 mg

15 mg

Liquid: 8.8 mg/5mL

Concentrated oral drops: 8.8 mg/mL

Syrup: 8.8 mg/5mL

Senna leaves:454g

Dosage Considerations – Should be Given as Follows:

Constipation


Adult: 15 mg orally once daily; not to exceed 70-100 mg/day divided every 12 hours

Not for use more than 1 week

Senna Leaf Extract

362-1056 mg orally once/day

Pediatric:

Children 2-6 years: 4.3-17.2 mg/day orally; not to exceed 17.2 mg/day

Children 6-12 years: 6-50 mg/day orally; not to exceed 50 mg/day

Children over 12 years: 12-100 mg/day orally; not to exceed 100 mg/day

Not for use more than 1 week

Senna Leaf Extract

2-6 years: 166.5-666 mg/day orally

6-12 years: 333-999 mg/day orally

Senna Leaf Extract Uses:

1.It can clear stomach and purge heat, defaecate and use diuretic of hydragogue to alleviate water retention;
2.It also helps to temporarily prevent fluid from being absorbed from the large intestine, thus contributing to softer stools;
3.It is used in the treatment of constipation, working through a stimulation of intestinal peristalsis.


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