Asarone, a component of the Asian traditional medicinal plant acorus calamus root extract, exhibited a variety of biological activities, including and effects. Acorus calamus extract and -asarone's in vitro effects on oxidative stress- and endoplasmic reticulum (ER) stress-induced cell death in hippocampal HT22 cells were the focus of this study.
L-glutamate, an oxidative stress inducer, and tunicamycin, an ER stress inducer, both induced cell death, and both acorus calamus root extract and -asarone significantly inhibited it.The l-glutamate-induced production of reactive oxygen species (ROS) was also significantly reduced by the extract of acorus calamus extract.
ITEM | STANDARD | TEST RESULT |
Specification/Assay | 10:1 | 10:1 |
Physical & Chemical | ||
Appearance | brown yellow powder | Complies |
Odor & Taste | Characteristic | Complies |
Particle Size | ≥95% pass 80 mesh | Complies |
Loss on Drying | ≤5.0% | Complies |
Ash | ≤5.0% | Complies |
Heavy Metal | ||
Total Heavy Metal | ≤10.0ppm | Complies |
Lead | ≤2.0ppm | Complies |
Arsenic | ≤2.0ppm | Complies |
Mercury | ≤0.1ppm | Complies |
Cadmium | ≤1.0ppm | Complies |
Microbiological Test | ||
Microbiological Test | ≤1,000cfu/g | Complies |
Yeast & Mold | ≤100cfu/g | Complies |
E.Coli | Negative | Negative |
Salmonella | Negative | Negative |
Calamusenone and camphene, two phytonutrients, are said to be abundant in acorus calamus extract.The first performs industrial functions as an emulsifier and surfactant.It is also involved in cell signaling, fatty acid metabolism, lipid peroxidation and metabolism, and lipid transport and metabolism.
Camphene is also a fragrance and a plant metabolite in the same way.In fact, acorus calamus root extract is utilized in toothpaste, shampoo, hair conditioner, body lotions, bathing soaps, and other personal care products due to its aromatic properties.It can take the place of traditional spices like ginger, cinnamon, and nutmeg due to its spicy and woody aroma.
According to the Personal Care Products Council's wINCI Dictionary, acorus calamus root extract even has a revitalizing role to play in personal care, specifically for moisturizing the skin. It is also widely used as an essential oil.Traditional medicine uses the acorus calamus extract to treat headaches, migraines, and other problems with the nervous system, according to one supplier.It is said to treat vertigo and dysentery symptoms, calm and relax the user, and reduce joint swelling.
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