What is Pinus Massoniana Bark Extract?
The Pinus Massoniana Bark Extract is a traditional Chinese medicine for the treatment of various health disorders. Previous studies have demonstrated that P. massoniana bark extract (PMBE) may induce the apoptosis of hepatoma and cervical cancer cells. However, whether PMBE is able to inhibit the migration of lung cancer cells requires further investigation. In the current study, the effects of PMBE on the viability of human lung cancer A549 cells were detected using an MTT assay. The migration of lung cancer cells following exposure to PMBE were quantified using wound healing and Transwell assays, respectively.
The expression levels of matrix metalloproteinase (MMP)‑9 were determined using western blotting. The results revealed that Pinus Massoniana Bark Extract significantly inhibited the growth of the lung cancer cells. In addition, the wound closure rate and the migration of the lung cancer cells were suppressed by PMBE. Furthermore, the expression levels of MMP‑9 were reduced. These findings indicated that PMBE is able to restrict the migration and invasion of lung cancer cells, and that PMBE may serve as a novel therapeutic agent for patients with metastatic lung cancer in the future.
Basic Information:
Specification of Pine bark Extract | |
Botanical Source: | Pinus Maritima Lamb. |
Part used: | Bark |
Specification: | 95% Proanthocyanidins |
Item | SPECIFICATION |
Description: | |
Appearance | Reddish brown fine Powder |
Flavor & Odor | Characteristic |
Particle size | 100% pass 80 mesh |
Physical: | |
Loss on Drying | ≤5.0% |
Bulk density | 40-60g/100ml |
Sulphated Ash | ≤5.0% |
GMO | Free |
General Status | Non-irradiated |
Chemical: | |
Pb | ≤3mg/kg |
As | ≤1mg/kg |
Hg | ≤0.1mg/kg |
Cd | ≤1mg/kg |
Assay: | |
Proanthocyanidins | ≥95% |
Microbial: | |
Total microbacterial count | ≤1000cfu/g |
Yeast & Mold | ≤100cfu/g |
E.Coli | Negative |
Staphylococcus aureus | Negative |
Salmonella | Negative |
Enterobacteriaceaes | Negative |
Pinus Massoniana Bark Benefits:
Alleviates oxidative stress by increasing the production of anti-oxidative enzymes that scavenge free radicals.
As an ,Pinus Massoniana Bark Extract can decrease the amount of circulating inflammatory substances in the blood stream.
Improves the absorption of other s, especially vitamins C and E.
Its activity improves the skin’s natural UV protection and gradual aging caused by the sun.
Promotes wound healing by improving circulation and calming inflammation.
Supports the immune system and helps to fight infection and prevent autoimmune responses, through a combination of , and activity.
: Pinus Massoniana Bark Extract has been shown to stave off staphylococcal, E. coli and pseudomonas bacterial infections.
Can reduce the risk of heart disease by lowering your levels of harmful cholesterol (LDL) and increasing good cholesterol (HDL).
May lower blood pressure and improve poor circulation. Pine bark extract helps the body to produce nitric oxide, which improves circulation and relaxes blood vessels to lower blood pressure.
Can help with varicose veins: a 2015 study showed that pine bark extract can improve circulation and reduce the swelling of varicose veins.
Anti-carcinogenic: studies indicate pine bark extract may be able to slow the growth of tumor cells in lung cancer and skin cancer.
Improves the health of the lungs. Pine bark extract has been shown to be effective in treating chronic lung disease.
Can treat and prevent loss of hearing and balance caused by ear infections or toxicity.
Can lower glucose levels in diabetics.
: reduces the symptoms of allergies by calming the auto-immune response.
effects in asthma
As an analgesic, it has been shown to help reduce menstrual cramps.
Promotes exercise endurance and reduces muscle fatigue in athletes, by reducing oxidative stress and therefore inflammation.
May help with erectile dysfunction, according to one Japanese study, without the side effects of conventional medications.
Can slow the progression of osteoarthritis, and reduce joint pain, mainly through its activity.
Can protect the eyes from retinal micro-haemorrhages, by increasing blood flow to the eyes.
May reduce your risk of cataracts: pine bark’s activity helps prevent cataracts and protects the eyes from the damaging effects of the sun.
May reduce your risk of Alzheimer’s by protecting neurons from beta-amyloid plaques in the brain.
Promotes healthy brain function. A 2011 Italian trial administered a pine bark extract supplement to students for eight weeks, resulting in improved concentration, memory and mood, and a decrease in anxiety levels. This was thought to be the result of improved blood flow to the brain. An earlier study showed improved memory in healthy elderly people, and reduced oxidative stress markers.
Pinus Massoniana Bark Extract Uses:
1. Pine bark powder is applied in pharmaceutical field, proanthocyanidins has better effect on the treatment of cardiovascular disease;
2. Applied in health products field , it's made into capsule. It has already become one of the ten salable natural plant extract products and owns the reputation of "natural health care product" and "orally cosmetics" in America;
3. Applied in food field, it can be used as food supplement;
4.Applied in cosmetic field, as the effective factor it was made into aqua or ointment cosmetics, which has the effect of firming skin, , and curing freckle.
The Best Pinus Massoniana Bark Extract Supplier
Undersun enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our products, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our products on-time.
We also focus on value-added services. We are available for service questions and information to support your business.
Why Choose Undersun Pinus Massoniana Bark Extract?
Undersun specialize in best pine bark extract for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.
Where to buy Pinus Massoniana Bark Extract?
For bulk wholesale nutraceutical pricing on Pine Bark Extract Powder or any other fruit, herb, spice & vegetable powder and powdered extract, please contact your ER representative directly or submit a wholesale quote request at email:[email protected].
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